Ovarian hypofunction is reduced function of the ovaries (including decreased production of hormones).
Ovarian hypofunction may be caused by genetic factors such as chromosome abnormalities. It may also occur with certain autoimmune disorders that disrupt the normal function of the ovaries. Chemotherapy and radiation therapy can also cause ovarian hypofunction.
Women with ovarian hypofunction may develop symptoms of menopause, which include:
Hot flashes
Irregular or absent periods
Mood swings
Night sweats
Vaginal dryness
Ovarian hypofunction may also make it hard for a woman to become pregnant.